Liver metastases of intrahepatic cholangiocarcinoma: implications for a potential new staging system
Intrahepatic cholangiocarcinoma (iCCA) with liver metastases (LM) are perceived to have a poor prognosis but the American Joint Committee on Cancer (AJCC) classifies them as early stage in the absence of lymph nodes or extrahepatic spread. This collaborative study including 574 and 4,171 patients from the ENS-CCA and SEER registries confirms that iCCA LM have a significant worse prognosis than other early stages and the authors suggest a novel “M1a stage” defined as liver metastasis: multiple liver lesions, with or without vascular invasion”
(Lamarca A, Santos-Laso A et al. Hepatology.18 October 2020)
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.